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Why no COVID-19 Vaccine quality Control in India?
What is the truth of Adenovirus virus vectored vaccines like CoviSheild, Sputnik V and Janssen and Janssen (The genetically modified (GM) vaccines)?
Though adenovirus vectors lack the ability to integrate into host chromosomes and are considered safe, studies have proven that the vector virus can integrate into our DNA and may induce alterations. The frequencies of integration and persistence of gene expression from integrated adenovirus vectors are∼10−3 to 10−5 per cell. That is it can integrate into one out of a thousand cells of your body or if 1000 virus vectors go to a cell one can integrate into the DNA of the cell. You can imagine that how many of your cells out of 15 Trillian cells may have got transformed DNA. And how many of about a billion adenovirus vectors injected in a dose of the COVID-19 vaccine can integrate into our DNA (about a million). It is also a proven fact that the integrated vector persisted for at least 50 cell divisions without selection. However, some stable cell clones showed changes in gene expression, which were accompanied by structural changes in the integrated vector DNA. (Though there are many, I am citing only one reference for your perusal https://jvi.asm.org/content/73/7/6141#:~:text=The%20structure%20of%20adenovirus%20DNA,adenovirus%20mutants%20at%20semi%2D%20or)
Tyranny is that
Nobody knows what may happen if adenovirus vectors got integrated into our cells. It can change the genome of your gametogenesis cells that is sperms or eggs may have an altered DNA or may induce cancer or many more things not imagined yet and not known due to lack of long term studies on their safety in humans.
Due to similar fears we have not permitted to grow and consume GM foods but are surrendering ourselves to be inoculated with GM vaccines like Covisheild and Sputnik V.
Most of the developed world countries has stopped the use of all such vaccines in their people of age less than 55 yrs including the UK which hold the patent rights of Covisheild. Then why India and many of the less developed countries are advocating its universal use?
Should we not have any such fear of mutations, do our people are lesser people than those living in the developed world or we not care about our coming generations?
https://www.researchgate.net/post/How_safe_are_Adenovirus_Vectored_vaccines_Do_such_vaccines_can_create_dangerous_integrations_in_your_DNAAbout safety of Killed/inactivated COVID-19 Vaccines
The biggest probable danger associated with the use of inactivated or killed Covid-19 vaccines (Covaxin, Sinovac V) is the spread of Covid-19 in the vaccinated population due to failure of the virus-killing or inactivation process. This is not an imaginary fear, it has happened several times after inoculation of FMD vaccines not only in India but also in Algeria after using India made FMD vaccine https://theprint.in/india/governance/indias-other-vaccine-mess-modi-govt-lost-hundreds-of-crores-on-faulty-shots-for-cows-in-2019-20/657274/).
Solution: Stringent quality control and assurance for each batch of the vaccine by an independent agency.
By the time it is too late, Drug Controller and Vaccine producers must start random sampling of Covid-19 vaccines at users end in light of the fact that every vital medicine and biological in India may be fraudulent or substandard. The minimum tests to ensure the required amount of antigen and proper inactivation of virus in the inactivated vaccines or required dose mRNA in mRNA vaccines or Carrier virus DNA quantification in vectored vaccines must be started immediately to avoid being all vaccination a futile exercise and waste of country funds. And the COVID-19 Control program may go the way NADCP (National Animal Disease Control Program for FMD and Brucellosis) India has already gone (https://theprint.in/india/governance/indias-other-vaccine-mess-modi-govt-lost-hundreds-of-crores-on-faulty-shots-for-cows-in-2019-20/657274/).
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