Wednesday, December 15, 2021
किसान आंदोलन की विजय के अर्थ
Tuesday, September 28, 2021
Impact of COVID-19 Vaccination on reduction of COVID-19 Cases and deaths during 14-27 September 2021
Global impact (expressed as correlation) of COVID-19 Vaccination
14-27 September 2021
For recent updates, you may view (https://www.researchgate.net/publication/357028670_Impact_of_COVID-19_Vaccination_on_COVID-19_Deaths)
Impact (expressed as correlation) of COVID-19 Vaccination in India
Cases and deaths due to COVID-19 in the
last 14 days (14-27 September 2021)
Analysis of data available online for COVID-19
cases & deaths, & % vaccination (Source: Source:
http://data.covid19india.org) for 28 states and 8 Union territories of India using a variable number
of dosages of three different vaccines of COVID-19 revealed that:
1.
More vaccination was linked with more deaths.
2. 1. The first dose of vaccine was associated with a significantly higher number of
Adverse Events
Following Immunization (AEFI), after 2nd dose, adverse events were
less.
3. 2. Adverse events were more often associated with CoviShield and less often
with Covaxin and Sputnik V.
4. 3. COVID cases and deaths were more in regions using more CoviShield (positive
correlation) than those using Covaxin and Sputnik V (negative correlation).
What to Do:
1. The immediate stoppage of the use of leaky, largely ineffective, and reactive COVID-19 Vaccines.
2. Promoting the development & use of whole virus vaccines either inactivated (like Sinopharm and Covaxin) or attenuated live (yet to be developed).
3. Promoting the judicious use of COVID-19 vaccines (https://azad-azadindia.blogspot.com/2021/03/how-judicious-is-covid-19-vaccination.html).
Herd-Immunity: A false notion for airborne and aerosol infections, not work well with the population moving and mixing with different groups frequently (Human population). After all, we are not herds of cattle or flocks of sheep to get advantages of herd immunity. It is a spoof floated by pharmacopoliticians to earn the money and bluff the people through creating panic and fear.
Wednesday, September 22, 2021
Impact of COVID-19 Vaccination on COVID-19 Cases and Deaths
Impact of COVID-19 Vaccination on COVID-19 Cases and Deaths
In the present analysis of data available for 208 countries with reference to a number of COVID-19 cases, deaths, population, etc. (https://www.worldometers.info/coronavirus) and vaccination (https://www.bloomberg.com/graphics/covid-vaccine-tracker-global-distribution/) was used to calculate the impact of vaccination using correlation and multiple regression techniques. The analysis of correlation was also narrowed down for the 28 countries all having populations of ≥50 million (Tab. 1). Though there may be several variables and confounders directly or indirectly affecting occurrence, spread, morbidity, and mortality of COVID-191-3 a successful vaccine and vaccination program is one which is little affected by regional or local, ethnic, and nonethnic, host and agent variables4-6. Successful eradication and control of several diseases including Polio, Smallpox, Rinderpest, and to some extent FMD and Brucellosis7. However, varying stands of National and International Health Agencies and Organizations indicated the mysteriousness8 of COVID-19 and maniac attitude of the system towards the diseases which also affect powerful and mighty people and nations9. Further, the Pharmacopolitical motives might have restricted scientists in understanding the therapeutics, pathology, and control of the disease to a great extent. The genetically modified vaccines developed through ill-tested and never before approved technologies with the human genome, the potential of inducing several life-threatening complications and probable mutations in germ cells with unknown dangers have been used for mass vaccination of global population10. Nobody knows or is not educated about the spread of disease and many false assumptions11 have been circulated, most probably intended to benefit a few big pharmaceuticals. Till 2019 the world health agencies were skeptical in permitting GM food production and consumption but suddenly the whole world has been inoculated with leaky GM vaccines with unknown efficacy and questionable safety converting vaccinated people to become super-spreaders (https://www.thehindubusinessline.com/news/national/mass-vaccinations-may-turn-super-spreaders-warn-kerala-docs/article35695823.ece) of the disease, the reasons might be known to the world health leaders.
The vaccines for protecting
from the COVID-19 in the world are leaky, i.e., they neither protect from getting
infection nor they provide enough immunity to halt virus multiplication in the
host body is associated with several vaccination-associated disorders making people
not only sick but also inducing life-threatening complications (https://www.cdc.gov/coronavirus/2019-ncov/vaccines/expect/after.html;
https://www.who.int/news-room/q-a-detail/coronavirus-disease-(covid-19)-vaccines-safety;
https://www.cdc.gov/coronavirus/2019-ncov/vaccines/safety/myocarditis.html; https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00467-9/fulltext)
The analysis
of online available data (1St September 2021) on vaccination in different countries and prevalence
and incidence of COVID-19 revealed that instead of reducing the incidence of
COVID-19 and mortality the vaccines in most of the countries are increasing the
disease occurrence and deaths due to it. The increasing rate of the vaccinated
population is having a positive impact on the increase in an absolute number of
COVID cases and deaths in statistically highly significant (p, ≤0.02) figures.
The level of association between vaccination percentage and increased number of
COVID cases per million and deaths per million is very strong (Tab. 2) in most
of the countries irrespective of the effect of population. However, a dilemma
is the low incidence and low mortality of the disease in China, one of the highly
vaccinated nations. In China, the vaccine used is a whole virus-killed vaccine
(Sinopharm). Are killed vaccines more effective than the vaccines developed
using modern biotechnology tools? The limited data on the simultaneous use of
different vaccines along with breakout cases and deaths in each group is highly
variable and not available in retrievable format in the public domain. In India,
three vaccines (Oxford AstraZeneca CoviShield, Covaxin, and Sputnik-V) have been
used at different levels of vaccination in different states and Union
territories (https://data.covid19india.org/). The data analysis (Tab. 3)
revealed that more use of Covaxin (a killed vaccine similar to that of
Sinopharm used in China) was associated with decreased incidence of cases and
deaths while the use of CoviShield was associated with an increased incidence of cases
and deaths in the respective state.
The analysis suggested that except for the killed vaccines, the use of COVID-19
vaccines is not only associated with adverse vaccine reactions but also with a significant increase in COVID-19 incidence and deaths due to COVID-19 in August
2021. The analysis may be criticized because of not excluding so many other
confounders affecting the outcome of vaccination, but the vaccines, efficacy of
which is affected with confounders, are almost useless and go to the dust with
time or remain as useful as Flu-Shots, only with limited and local use. Thus,
there is an urgent need for research in therapeutics and also towards the development of more effective vaccines. Though personally, I am skeptical of the
vaccine efficacy due to inherent short-lived immunity after vaccination as well
as after natural infection.
The analysis further shattered the hopes from much-expected
Herd-Immunity (>70% vaccination), as even after achieving the magic figure
and much more, emerging mutants (as Delta and Mu; either under the effect of
partial vaccination or global presence of the disease have evaded all kinds of
immunity faultily measured by antibody response.
References
1. Bhoj
R. Singh et al.
Epidemiological Determinants of Acute Respiratory Syndrome Coronavirus-2
Disease Pandemic and The Role of the Bacille-Calmette-Guerin Vaccine in
Reducing Morbidity and Mortality. Journal of Pure and Applied
Microbiology 2020(14):6224. DOI: 10.22207/JPAM.14.SPL1.39.
2. Bhoj
R. Singh et al. Are BCG
Vaccination, Population Density, Median Age and Poverty Important Determinants
of COVID-19 Pandemic Spread, Morbidity and Mortality? DOI: 10.13140/RG.2.2.21116.49282.
3. Bhoj
R. Singh. Changing Relations
of COVID-19 Morbidity, Mortality, and CFR with the World. DOI: 10.13140/RG.2.2.17870.89925/2.
4.
Bhoj R. Singh., et al. Pros and Cons of
Covid-19 vaccines and vaccination DOI:10.12032/IDR2021B0207001
5. Bhoj
R. Singh., et al. COVID-19
Vaccines and Community Immunity. Infectious Diseases: Research and
Treatment 2(1):5. DOI: 10.12032/IDR2021B0207001
6. Bhoj
R. Singh. Epidemiology of
COVID-19 Pandemic and its Control strategies. DOI: 10.13140/RG.2.2.22268.28808/1
7. Bhoj
R. Singh., et al. “Science Behind Non-spreading of COVID-19 During and After
Political Rallies". Acta Scientific Pharmacology 2.6 (2021):10-16.
8. Bhoj
R. Singh. The COVID-19: A
Mystery Disease. DOI: 10.13140/RG.2.2.19214.89921
9.
Bhoj R. Singh. “COVID Mania and Truth of
Life". Acta Scientific Pharmacology 1.9 (2020): 41-42.
10.
Bhoj R. Singh. Why sceptical of recommending the use of COVID-19
vaccines in the reproductive age? DOI: 10.13140/RG.2.2.24405.14565/1.
11. Bhoj
R. Singh. The Unwinding of
the Second COVID-19 Wave in India. DOI: 10.13140/RG.2.2.28062.25920
Saturday, July 10, 2021
India: The World’s most Corporate (Pharma) Friendly Nation Part 2: Pharmacoplitics: Medical Oxygen and Covid-19 Vaccines are not Tested for Quality
India again proved that it is the World’s most Pharma-Corporate Friendly Nation
Medical Oxygen and Covid-19 Vaccines are not Tested for Quality
Government by the Corporates, for the Corporates through Pharmacopolitics to bleed the people!!!
An RTI CDSCO/R/E/21/00235
Reply from The Central Drugs Standard Control Organisation (CDSCO), the organization responsible to Ensure and Guarantee Quality drugs, vaccines and other medical supplies to Indians revealed that:
Except for samples of 14 batches of COVID-19 vaccines collected in the Hyderabad region of CDSCO, not a single batch of 18 of #SputnikV, 117 of #COVAXIN & 153 of #COVISHIELD released in India from January to 30 June 2021 was sampled by CDSCO for #Quality_testing or #Quality_Tested.
Samples are claimed to be tested at CRI Kasauli for all 288 batches released till June 2021 for use in India, if not collected by CDSCO might have been sent from the producers or suppliers for getting clearance. Anyone can understand the validity of such sampling, no producer or supplier send substandard samples for testing. If sampling is not done at users end by CDSCO, directly under Central Government Control in the Department of Health and Family Welfare, it indicates the facilitation of Pharmaceuticals producing and supplying Covid-19 vaccines and there is no difficulty in understanding what may be the purpose for the facilitation may be.
None of the batches of millions of tones of #Medical_Oxygen supply released in India from January to 30 June 2021 was sampled by CDSCO for #Quality_testing or #Quality_Tested.
This clearly revealed that Indian organizations work for corporate houses not for people. It is a false notion that India has a "Government is of people, by the people, for the people". It is only for the big corporate houses funding some selected. Government by the Corporates, for the Corporates through Pharmacopolitics to bleed the people!!!
Wednesday, May 12, 2021
Why no COVID-19 Vaccine quality Control in India? The truth of Adenovirus virus vectored vaccines as CoviSheild, Sputnik V and Jensen and Jansen, The genetically modified (GM) vaccines.
Share your views, please.
Monday, March 22, 2021
How judicious is the COVID-19 Vaccination? कोविड-१९ टीकाकरण में कितनी समझदारी है?
How judicious is
the COVID-19 Vaccination?
कोविड-१९ टीकाकरण में कितनी समझदारी है?
The facts
1.
The
natural infection of most of the diseases if not lethal provide immunity:-
a.
Longer
lasting immunity (always longer than afforded by any of the good vaccines).
b.
Provides
Cross-protection against most of the variants (vaccine often fails at this
front).
2.
Vaccines
can put those at the risk (though very less than the natural infection) who are
either not exposed to the infection or have no chance of getting the infection.
3.
None
of the COVID-19 vaccine is tested for long term safety, stability, potency and
longevity of the immunity afforded. Yes, short term studies have shown them
safe. No testing in special target groups like those want to have kids in future, kids and specially-abled people.
4.
Most
of the COVID-19 vaccines are genetically engineered (modified) but released into the market (in haste looking at the market ‘hot-cakes demand) and injected
into our body without any hitch but advocated by all world authorities. However,
genetically modified foods (GM Foods) are still not permitted to be eaten in
most countries which are supposed to have a much lesser risk of modifying our genes
and disturbing the environment. To me, it is the short cut permission to GM type of half tested
vaccines that may pave the way to the release of GM foods in future.
5.
For most of the poor people of the world COVID-19 vaccine is not affordable and
will remain so.
6.
Nobody
knows and not approve the superiority of one vaccine over the others (about
half a dozen are available in the world market). That means all the vaccine are
either equally effective or equally ineffective, both are the false statements
only.
7.
Any
of the vaccine is neither being used to generate herd immunity (evident by the
vaccination program implementation) nor to protect masses but all can afford
some personal protection and benefit the pharmaceutical market.
8.
It
is claimed that immunity of COVID-19 vaccine after booster dose can last for three
to ten months. Probably no country will be able to vaccinate its population
that frequently even after payment by the people (almost impossible for most of
the big and poor countries) that means there is no chance of generation of COVID-19
immune community or the immune world.
9.
The world is in short supply of the COVID-19 vaccine and expected to remain.
10.
Cold
chain required for maintenance of the COVID-19 vaccines is certain to fail in
most parts of the world thus the vaccine and vaccination both.
11.
Majority
of the people in many of the countries are reluctant to have COVID-19
vaccination even in a developed and educated world so no question arises for
achieving herd immunity.
12.
Hardly
15 in 1000 of exposed get sick of COVID-19 (without any vaccination) and of the
100 sick a few (3-5) need hospitalization and 3-5% of those hospitalized have
chance to die of COVID-19. What this mathematic tells us: Out of one million
people about 300 to 400 have the chance of death due to COVID-19 even after exposure
to the infection.
13.
Three
to five people of every million people receiving COVID-19 vaccine are supposed
to die due to anaphylaxis leading to death i.e., deaths due to COVID-Vaccine
instead of COVID-19 disease are almost 1%. The other problems and complications
of COVID-19 vaccines are there in the high frequency which you may never have if
avoid getting an infection or have frequent COVID-19 infection after surviving the
first one (as each infection afterwards acts as a booster.
14.
Generation
of mutants or variants of COVID-19 virus is destiny in a partially immune
population and a day will come when all the present-day COVID-19 vaccine will
be almost useless as the antibiotics are. However, as the market driving forces
have kept the antibiotic market still the biggest pharmaceutical market similar
factors may keep up the demand for all (useless/ useful/ fake/ substandard)
COVID-19 vaccines. It is already evident by a few variants now emerging as the dominant cause of the disease with higher spreadability, morbidity and mortality on which the vaccines in the market have already been shown of no or of little value.
15.
Humanity
has to survive and will survive even without any of the vaccines despite thousands
of diseases for which we have and don’t have the vaccines.
So what should be
done for judicious use of vaccine?
1.
Protective
antibody assay should be conducted on all to be vaccinated using some onsite
rapid test before vaccinating.
2.
The
people who have recovered from COVID-19 infection and have protective immunity
should not be vaccinated to save precious dosages of the vaccine.
3.
The
people who have protective immunity should be allowed to move free of mask so
that they can get natural boosters for maintaining their immunity.
4.
Immune
people (either after recovery or after vaccination) should only be allowed to
work in offices and in public (Almost impossible for election states).
5.
All
shop-keepers, vendors, labourers, bank employees, veterinarians must be
vaccinated on priority, in reality, they all are the front line workers. Medicos
and policeperson too are front line workers but well educated to handle such
situations and can afford to take their care to avoid getting and spreading infection.
The best option for COVID-19 Control with vaccination
There should be no vaccination till we are ready to vaccinate the whole world within a short period of three months (i.e., in one go) to have Herd-Immunity at a given point of time otherwise Epidemiological studies in past had proved that partial herd-immunity is more dangerous in disease control strategy as it leads to the emergence of variants and mutants with increased pathogenic potential. The emergence and fast spread of more dangerous strains of COVID-19 in the last 3-4 months have proved it. The half-hearted or midway approach leads to the establishment of a disease as an endemic where high and low waves of local epidemics of the disease are certain to be seen.
For More details: https://www.researchgate.net/publication/348192258_Pros_and_Cons_of_Covid-19_vaccines_and_vaccination/stats